31 Jan Ovarian PRP: What Does the Evidence Really Say?
Ovarian rejuvenation using Platelet-Rich Plasma (PRP) has been making waves in the fertility world over the past few years. It’s an exciting concept for women struggling with low ovarian reserve, early menopause, or fertility challenges. At Pelargos IVF, we’re always on the lookout for innovative treatments to help our patients achieve their dreams of parenthood, and PRP therapy is one option that’s getting a lot of attention. But what exactly is ovarian PRP, and how effective is it? In this guide, we’ll break it all down, sharing everything from the science behind it to what the research says.
What Is Ovarian PRP Therapy?
Ovarian PRP therapy is a procedure that uses your own blood to extract plasma rich in growth factors, which is then injected into the ovaries. These growth factors are believed to stimulate ovarian tissue, potentially improving egg quality and number, as well as hormone production. At Pelargos IVF, we see PRP therapy as a way to give new hope to women who feel like their options with their own genetic material are running out. While it’s not a guaranteed solution, it’s a step forward in fertility science that’s worth exploring.
Who Might Benefit from Ovarian PRP?
Ovarian PRP might be a good option for: Women with Low Ovarian Reserve: If tests show low AMH or high FSH levels, PRP could help improve ovarian function, hormonal profile, or antral follicular count. Early Menopause: Women with premature ovarian insufficiency (POI) may benefit. Age-Related Fertility Decline: For women over 40, with or without low ovarian reserve, PRP offers another option to boost ovarian activity and potentially improve quality. Failed IVF Cycles: If previous IVF cycles haven’t worked, PRP might improve your response to treatment.
How Does the Procedure Work?
The PRP process is relatively straightforward: Blood Draw: A small amount of your blood is taken. PRP Extraction: The blood is processed (centrifuged) to separate out the platelet-rich plasma. Injection into the Ovaries: Using ultrasound guidance, the PRP is carefully injected into the ovaries. At Pelargos IVF, we also offer the option of PL PRP, which involves centrifuging the blood at a higher speed to break down the platelets, releasing an enzyme called Platelet Lysate (PL). This creates an injection sample with a higher concentration of cytokines and growth factors. Recovery: It’s a minimally invasive procedure, and most women resume normal activities within the same day. At Pelargos IVF, we perform this procedure with the utmost care and attention to ensure your comfort and safety throughout the process.
What Does the Research Say?
So, does ovarian PRP actually work? Let’s take a closer look at the evidence: Hormone Levels: Studies suggest that PRP can help increase AMH levels and lower FSH, two key indicators of ovarian health. Egg Quality and Quantity: Some research shows that PRP may improve the number and quality of eggs retrieved during IVF cycles, though statistical proof is still lacking. Natural Conception: There are cases where women conceived naturally after PRP treatment, even when other options seemed out of reach. While these findings are promising, it’s important to note that PRP is still considered experimental. Success rates vary depending on factors like age and individual health, and more research is needed to establish long-term benefits.
Why Choose Pelargos IVF for Ovarian PRP?
At Pelargos IVF, we’re proud to offer cutting-edge treatments like PRP therapy to give our patients the best possible chance of success. Here’s what sets us apart: Personalized Care: Every patient’s journey is unique, and we tailor treatments to suit your specific needs. Expertise: Our team stays up to date on the latest fertility advancements, ensuring you’re in the best hands. Supportive Environment: We know how emotionally challenging fertility struggles can be. That’s why we’re here to support you every step of the way.
Is Ovarian PRP Right for You?
PRP isn’t for everyone, but it might be worth considering if you’re looking for new options to improve your fertility. The best way to find out is to book a consultation with one of our specialists at Pelargos IVF. Together, we’ll discuss your history, goals, and whether PRP could be the right fit for your journey.
Conclusion
Ovarian PRP is an exciting and innovative treatment that offers hope to women facing tough fertility challenges. While the evidence is still evolving, it’s a step forward in the world of fertility medicine. At Pelargos IVF, we’re committed to helping our patients explore every option available to achieve their dreams of parenthood. If you’re curious about ovarian PRP or want to learn more about how we can help, reach out to us at Pelargos IVF today. We’re here to guide you every step of the way.
References
Sfakianoudis, K., Simopoulou, M., Grigoriadis, S., Pantou, A., Tsioulou, P., & Pappas, A. (2019). Reactivating ovarian function through autologous platelet-rich plasma intraovarian infusion: Pilot data on premature ovarian insufficiency and low ovarian reserve. Frontiers in Endocrinology, 10, 866. https://doi.org/10.3389/fendo.2019.00866
Pantos, K., Simopoulou, M., Rapani, A., Grigoriadis, S., & Tsioulou, P. (2020). Innovative strategies in overcoming low ovarian reserve: The role of ovarian rejuvenation. Journal of Assisted Reproduction and Genetics, 37(8), 1849–1855. https://doi.org/10.1007/s10815-020-01849-w
Garcia-Velasco, J. A., & Fatemi, H. M. (2015). Ovarian rejuvenation: The need for more data and less speculation. Fertility and Sterility, 104(5), 1200–1201. https://doi.org/10.1016/j.fertnstert.2015.08.023
Cairo Consensus Group. (2022). Current and future applications of ovarian PRP: A position statement. Reproductive BioMedicine Online, 45(2), 97-102. https://doi.org/10.1016/j.rbmo.2022.04.003
Esteves, S. C., Roque, M., & Garcia-Velasco, J. A. (2020). Novel strategies for poor ovarian response: From ovarian stimulation protocols to stem cell therapies. Fertility and Sterility, 113(4), 645–654. https://doi.org/10.1016/j.fertnstert.2020.01.017
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